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Cobiostab 400 5 ml

Why a small preservative sample matters before scaling up a formula

Water-based cosmetic products such as creams, lotions, serums and gels create a favorable environment for bacteria, yeast and mold unless they are properly protected against microbial contamination. Cobiostab 400 belongs to the category of preservatives and antioxidants, which gathers ingredients aimed at protecting formulations from microbial spoilage and oxidative degradation. The 5 ml pack size is aimed at home formulators, indie brand owners and small labs who want to test a new recipe or fine-tune the dosage before ordering a larger volume of raw material.

Cobiostab 400 is a liquid broad-spectrum preservative effective against gram-positive and gram-negative bacteria as well as yeasts and molds. It is widely used in skin and hair care emulsions, decorative cosmetics, shampoos, conditioners, gels, wet wipes and other water-containing household chemical products. The preservative performs reliably across a wide pH range and is compatible with most active ingredients, including plant extracts, hydrosols, vitamins and oils, which makes it a convenient tool for formulators experimenting with new compositions.

Recommended usage typically ranges from 0.5 to 1.5 percent of the total formula weight, depending on the water content, emulsion type and desired shelf life. The preservative is added at the final stage of production once the base has cooled to no higher than 40 degrees Celsius, since excessive heat can reduce the effectiveness of its active components. Thorough mixing before addition ensures even distribution throughout the entire batch.

Cobiostab 400 is often combined with other protection systems to broaden the antimicrobial spectrum and improve formula reliability. Pairing it with antioxidants further protects the oil phase from rancidity, while combining it with Cosphaderm LEO helps cover a wider range of microorganisms in more complex recipes. For formulators working on milder or naturally derived formulas, an interesting option is pairing it with the plant-based preservative Leucidal Liquid Complete, which is often positioned as an alternative to synthetic protection systems. It is also worth considering Mikrokill ЕСТ, which is frequently used alongside Cobiostab 400 to boost stability in water-rich emulsions.

The preservative should be stored in a tightly closed container, in a cool dark place away from direct sunlight and heat sources, protected from moisture and contamination. Under proper storage conditions, the product retains its stated effectiveness throughout the manufacturer's shelf life. The small pack size is convenient because it allows the contents to be used up quickly, avoiding any loss of activity that can occur with long-term storage of an opened larger container.

Before moving a recipe into serial production, it is advisable to run a microbiological challenge test of the finished product in an independent laboratory to confirm that the chosen preservative dosage is sufficient for the intended storage and usage conditions. This is especially important for products that come into contact with water during use, such as hand creams or cleansing gels.

Lightweight facial serum with preservative protection

Distilled water 70 g

Aloe vera juice 10 g

Glycerin 4 g

Hyaluronic acid solution 4 g

Panthenol 3 g

Water-soluble oil complex 3 g

Cobiostab 400 1 g

Fragrance or essential oil 0.3 g

Date:

today

Author:

Шарлотта, Дрезден

Reviews

Я вже не раз замовляла тут різні інгредієнти, і завжди залишалася задоволена. Якість завжди на висоті, а доставка швидка. Дякую вам за вашу роботу!

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Алина, Тараща

Очень довольна покупкой! Брала базовые и эфирные масла. Все понравилось, буду заказывать еще.

1 August 2026

Света, Свалява

Замовила олії для волосся. Якість чудова, результат помітний. Волосся стало більш блискучим і міцним. Результатом дуже задоволена!

INCI	Propylene Glycol (and) Hexamidine Diisothionate
Other
Application	scrubs, creams, shampoos, balms, conditioners, masks
Att brand	Poland
Color product	amber
Concentration	Recommended: 0.6% - 2.5%
Features	All information presented on the site is for reference only
Input percentage	0.6 to 2.5%
Intended use	cosmetics
Minimum count	1
Name	Cobiostab 400 5 ml
Packaging	container for transportation
Packing	5 ml
Solubility	water soluble
Type	preservative, biocide
View	liquid
Valid until	04.2028