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Enzymes, Filtrates, and Lysates
Biotechnological ingredients for advanced skincare formulation
This section brings together enzymes, ferment filtrates, and lysates used as functional additives in cosmetic formulation. These ingredients originate from controlled biotechnological processes involving yeast, bacterial cultures, plant tissue, or algae, and they arrive as concentrated raw materials ready to be blended into a finished cosmetic base at defined percentages.
Formulators use these components across a wide range of product types rather than a single niche application. Enzymes can support the breakdown of specific substrates within a formula, while ferment filtrates and lysates are typically included for their biologically active fraction, contributing to how a cream, serum, essence, or emulsion performs on the skin. You will find them in leave-on facial care, lightweight serums, night treatments, and body emulsions alike, chosen for the particular biochemical profile each culture or tissue source provides. Explore related functional components to combine with these ingredients, or browse the wider cosmetic ingredients catalog for complementary raw materials.
Enzymes, ferment filtrates, and lysates: what sets them apart
Within this category, enzymes are typically supplied as isolated proteins that catalyze a specific reaction inside a formula, such as supporting the turnover of surface material on skin. Ferment filtrates, by contrast, are the liquid fraction left after a controlled fermentation process, carrying a broad mix of metabolites, peptides, and micronutrients rather than a single active molecule. Lysates come from ruptured cells, releasing intracellular contents that formulators value for their concentrated biological fraction.
A product like Zymo Clear MD 5 g illustrates how an enzymatic ingredient can be positioned for clarifying and refining formulas, while something like PREBIULIN C90 5 g works from a different angle, supporting the skin surface microenvironment within leave-on and rinse-off bases alike.
Choosing a raw material and building compatible blends
Selection usually starts with the intended finished product: a lightweight essence calls for a highly soluble, low-viscosity input, while a richer night cream or body emulsion can absorb a more concentrated fraction without disrupting texture. Recommended usage percentage, pH stability range, and solubility profile are the three parameters formulators check first before adding any of these ingredients to a batch.
Antioxidant-driven actives are frequently paired with this group to extend formula stability. ACB Olive Leaf Extract PF 10 ml and Superoxide Dismutase Powder SOD 2 g are both commonly combined with enzymes and filtrates to balance oxidative stress within the same base. For texture and barrier-support goals, Bonicel 5 ml and Celldetox 5 ml are often layered into hand, face, or body emulsions alongside a fermentation-derived component, while Vaccinium Myrtillus Extract filtrate 10 ml adds a plant-based filtrate profile that blends well into firming and smoothing formulas.
Origin, format, and storage
Raw materials in this section arrive from established biotechnology and specialty ingredient producers in Italy, the United States, France, and the Netherlands, each contributing a slightly different cultivation or fermentation methodology behind the final concentrate. Most are supplied in small-volume vials or powder sachets, sized for accurate dosing in both pilot batches and larger production runs.
Because enzymes and ferment filtrates are biologically active, refrigerated storage away from direct light is generally recommended to preserve potency between uses. For a broader raw material base to round out a formulation, the Bulk Waxes for Cosmetics section offers structuring components that pair well with these active fractions in creams and balms.
FAQ
What is the difference between an enzyme and a ferment filtrate in cosmetic raw materials
An enzyme is an isolated protein that catalyzes a specific reaction within a formula, while a ferment filtrate is the filtered liquid remaining after a culture has grown and metabolized its medium, carrying a broader mix of metabolites, peptides, and sugars from that biological process.
Can enzymes and lysates be combined with other active ingredients in one formulation
Yes, these ingredients are commonly blended with humectants, emollients, and other functional actives. Compatibility depends on pH, temperature stability, and the percentage used, so it is best to trial a small batch before scaling up a full production run.
How should ferment filtrates and lysates be stored before use
Keep containers tightly closed, away from direct light and heat, ideally in a cool, dry storage area. Some lysates and filtrates are sensitive to temperature swings, so checking supplier guidance for the specific culture source is recommended before long term storage.
What percentage of enzymes or ferment filtrates is typically used in a formula
Usage levels vary widely depending on the specific ingredient and desired effect in the finished product, commonly ranging from a fraction of a percent up to a few percent of the total formula. Always start with a small test batch to confirm performance before full scale production.
Recommendations
When selecting an enzyme, ferment filtrate, or lysate for a specific formulation, consider the biological source, the intended texture of the finished product, and how the ingredient behaves at your target pH and temperature range. Request a small trial quantity first to confirm stability and skin feel before committing to a larger batch. Our team is available by email to help match a raw material to your production needs and confirm current stock for the volume you require.



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