LPA (Lysophosphatidic Acid, Japan) — lipid-based active for skin regeneration and firming
LPA (Lysophosphatidic Acid) is a next-generation bioactive ingredient developed in Japan, known for its ability to stimulate cellular regeneration, restore skin density, and enhance dermal architecture. As a natural phospholipid derivative, LPA acts as a signaling molecule, triggering key processes such as keratinocyte differentiation, hyaluronic acid synthesis, and tissue repair.
Recognized for its efficacy even at low concentrations, LPA is ideal for premium anti-aging skincare. It strengthens the skin barrier, boosts hydration retention, and promotes a firmer, more youthful appearance. Its lipophilic nature allows it to penetrate skin layers effectively, making it an excellent addition to advanced serums, ampoules, and dermo-cosmetic formulations.
Uses and benefits in cosmetic products
LPA is suitable for:
anti-aging serums and firming face creams
intensive ampoule treatments and lifting programs
formulations for neck, décolleté, lips, and facial contour
skin-repair products after peels, lasers, or sun exposure
creams for stressed, thinning, or dehydrated skin
professional-grade post-procedure care
By activating cell receptors, Lysophosphatidic Acid promotes the production of hyaluronic acid, collagen, and key structural elements of the extracellular matrix. It supports visible skin thickening, smoother texture, and long-term rejuvenation without irritation.
Formula: Regenerating face serum with LPA
LPA (1% solution) — 3 g
Low molecular weight hyaluronic acid — 0.3 g
Rose hydrosol — 40 ml
Panthenol — 2 g
Niacinamide — 4 g
Fermented laminaria extract — 1 g
Dermosoft OMP preservative — 1 g
Distilled water — up to 100 ml
Add LPA during the final phase. Mix all water-based ingredients, introduce actives and adjust pH to 5.0–5.5. The finished serum absorbs quickly, delivers lasting hydration, firms the skin, and improves elasticity over time.
Conclusion
LPA (Lysophosphatidic Acid) is a powerful Japanese-origin lipid active that addresses skin aging at a cellular level. It strengthens skin structure, enhances elasticity, and delivers visible lifting and rejuvenation benefits. Perfect for high-performance skincare, professional treatments, and innovative clean beauty products.
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