Ketoconazole 1 kg

Antifungal Powder Behind Modern Dandruff and Scalp Care Formulas

Ketoconazole is best known as a potent antifungal ingredient used extensively in the manufacture of specialized shampoos, lotions, and scalp treatments designed to combat dandruff, seborrheic dermatitis, and excessive activity of Malassezia yeast on skin and scalp. This raw material belongs to the Biocides category, which brings together substances that suppress the growth of microorganisms and fungal microflora across cosmetic and pharmaceutical formulations. The 1 kg pack size fits studio-scale and small-batch manufacturing perfectly, supporting laboratories and cosmetic workshops that need a reliable, repeatable supply for regular production runs of specialized scalp care lines.

The primary industrial use of ketoconazole spans cosmetic and pharmaceutical manufacturing: it forms the active base of anti-dandruff shampoos, creams and gels for problematic skin, and preventive treatments against fungal conditions of the scalp and body. In practice, formulators often pair it with supporting functional ingredients such as amino acids like Alanine 1 kg or Methionine 1 kg, which support scalp and hair condition alongside the antifungal action of the main component. Ketoconazole is also frequently combined with antiseptic agents such as Chlorhexidine digluconate 20% 1 kg to reinforce the overall protective profile of a formula against both bacterial and fungal contamination.

Typical dosage in finished formulations ranges between 1 and 2 percent of the total batch weight, depending on the intended purpose of the product and the required strength of the active substance. The ingredient should be introduced during the cooling phase of the batch, at a temperature not exceeding 40-45 degrees Celsius, to prevent thermal degradation of the active compound during prolonged heat exposure. It is advisable to pre-disperse the powder in a small amount of a base solvent or surfactant before adding it to the main mixture, ensuring even distribution throughout the product and preventing clumping.

Compatibility with common cosmetic bases is well established: ketoconazole works reliably in water-alcohol systems, emulsions, gel bases, and micellar formulas. When developing a recipe, it is important to keep the finished product's pH stable and avoid sharp acidity shifts that could reduce the ingredient's effectiveness. Beyond shampoos and scalp treatments, this component also finds use in veterinary topical products, animal care formulations, and certain household chemical products requiring antifungal protection.

Store ketoconazole in a dry area away from direct sunlight, at room temperature, in a tightly sealed container that prevents moisture ingress. Under proper storage conditions the ingredient retains its activity for an extended period, making the 1 kg pack a cost-effective choice for manufacturers running consistent, repeated production cycles.

Strengthening Anti-Dandruff Shampoo Base

Ketoconazole 20 g

Sulfate-free shampoo base 900 g

Methionine 5 g

Alanine 5 g

Chlorhexidine digluconate 20% 3 g

Distilled water 67 g